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A LuxR ‐type repressor of B urkholderia cenocepacia inhibits transcription via antiactivation and is inactivated by its cognate acylhomoserine lactone

9 Nov 2012

Abstract excerpt

Burkholderia cenocepacia is an opportunistic human pathogen that encodes two LuxI-type acylhomoserine lactone (AHL) synthases and three LuxR-type AHL receptors. Of these, cepI and cepR form a cognate synthase/receptor pair, as do cciI and cciR, while cepR2 lacks a genetically linked AHL synthase gene. Another group showed that a cepR2 mutant overexpressed a cluster of linked genes that appear to direct the...

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PMID: 23136852
DOI: 10.1111/mmi.12085

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