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Article

Characterization of a novel two-component system in Burkholderia cenocepacia.

Current microbiology - 1 Apr 2015

Merry Callie R, Perkins Michael, Mu Lin, Peterson Bridget K, Knackstedt Rebecca W, Weingart Christine L

Abstract excerpt

Two-component systems are important regulatory systems that allow bacteria to adjust to environmental conditions, and in some bacteria are used in pathogenesis. We identified a novel two-component system in Burkholderia cenocepacia, an opportunistic pathogen that causes pneumonia in cystic fibrosis (CF) patients. The putative operon encodes BceS, a sensor kinase, and BceR, a response regulator. Our studies...

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PMID: 25519693
DOI: 10.1007/s00284-014-0744-z

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