Article
Bitter taste receptor polymorphisms and human aging.
PloS one - 1 Jan 2012
Campa Daniele, De Rango Francesco, Carrai Maura, Crocco Paolina, Montesanto Alberto, Canzian Federico, Rose Giuseppina, Rizzato Cosmeri, Passarino Giuseppe, Barale Roberto
Abstract excerpt
Several studies have shown that genetic factors account for 25% of the variation in human life span. On the basis of published molecular, genetic and epidemiological data, we hypothesized that genetic polymorphisms of taste receptors, which modulate food preferences but are also expressed in a nu...
Topics
- Adult
- Aged
- Aged, 80 and over
- Aging
- Food Preferences
- Genetic Variation
- Genotype
- Haplotypes
- Homozygote
- Humans
- Italy
- Longevity
- Middle Aged
- Models, Genetic
- Multigene Family
- Polymorphism, Single Nucleotide
- Receptors, G-Protein-Coupled
- Taste