Article
A derivative of L-allo threonine alleviates 2,4-dinitrofluorobenzene-induced atopic dermatitis indications.
Bioscience, biotechnology, and biochemistry - 1 Jan 2012
Heo Jin-Chul, Son Hyeong-U, Kim Solomon L, Lee Sang-Han
Abstract excerpt
LX519290, a synthetic derivative from a combinatorial chemistry library, has been screened for anti-atopic activity, but its biological activities have not yet been elucidated. To assess whether LX519290 has the potential to lessen 2,4-dinitrofluorobenzene-induced atopic dermatitis symptoms in mice, first we sensitized the skin in the dorsal neck of C57BL/6 mice and re-sensitized the ear skin to determine the ear...
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