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Article

Yeast importin-β is required for nuclear import of the Mig2 repressor.

BMC cell biology - 6 Nov 2012

Fernández-Cid Alejandra, Vega Montserrat, Herrero Pilar, Moreno Fernando

Abstract excerpt

BACKGROUND: Mig2 has been described as a transcriptional factor that in the absence of Mig1 protein is required for glucose repression of the SUC2 gene. Recently it has been reported that Mig2 has two different subcellular localizations. In high-glucose conditions it is a nuclear modulator of several Mig1-regulated genes, but in low-glucose most of the Mig2 protein accumulates in mitochondria. Thus, the Mig2...

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Identifiers

PMID: 23131016
DOI: 10.1186/1471-2121-13-31
PMCID: PMC3531251

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