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Article

A zebrafish phenotypic assay for assessing drug-induced hepatotoxicity.

Journal of pharmacological and toxicological methods - 1 Jan 2000

He Jian-Hui, Guo Sheng-Ya, Zhu Feng, Zhu Jun-Jing, Chen Yun-Xiang, Huang Chang-Jiang, Gao Ji-Min, Dong Qiao-Xiang, Xuan Yao-Xian, Li Chun-Qi

Abstract excerpt

INTRODUCTION: Numerous studies have confirmed that zebrafish and mammalian toxicity profiles are strikingly similar and the transparency of larval zebrafish permits direct in vivo assessment of drug toxicity including hepatotoxicity in zebrafish. METHODS: Hepatotoxicity of 6 known mammalian hepat...

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Share to Chemical and Drug Induced Liver Injury
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Identifiers

PMID: 23128142
DOI: 10.1016/j.vascn.2012.10.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23128142-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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