Article
Practical capability and cost effectiveness of a DNA pool-based genome-wide association study using BovineSNP50 array in a cattle population.
Animal science journal = Nihon chikusan Gakkaiho - 1 Nov 2012
Uemoto Yoshinobu, Sasago Nanae, Abe Tsuyoshi, Okada Hideki, Maruoka Hitomi, Nakajima Hiroaki, Shoji Noriaki, Maruyama Shin, Kobayashi Naohiko, Mannen Hideyuki, Kobayashi Eiji
Abstract excerpt
Genome-wide association mapping for complex traits in cattle populations is a powerful, but expensive, selection tool. The DNA pooling technique can potentially reduce the cost of genome-wide association studies. However, in DNA pooling design, the additional variance generated by pooling-specific errors must be taken into account. Therefore, this study aimed to investigate factors such as: (i) the accuracy of...
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