Article
Genome-wide association studies: inherent limitations and future challenges.
Frontiers of medicine - 1 Dec 2012
Du Yan, Xie Jiaxin, Chang Wenjun, Han Yifang, Cao Guangwen
Abstract excerpt
Genome-wide association studies (GWAS) have achieved great success in identifying genetic variants related to complex human diseases such as cancer and have provided valuable insights into their genetic architecture. Recently, GWAS is quite the fashion in China. However, there are issues related to its nature. Enormous work needs to be done in the post-GWAS era. Deep sequencing followed by functional studies will...
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