Article
Brief Report: Single-nucleotide polymorphisms in VKORC1 are risk factors for systemic lupus erythematosus in Asians.
Arthritis and rheumatism - 1 Jan 2013
Kaiser Rachel, Taylor Kimberly E, Deng Yun, Zhao Jian, Li Yonghong, Nititham Joanne, Chang Monica, Catanese Joseph, Begovich Ann B, Brown Elizabeth E, Edberg Jeffrey C, McGwin Gerald, Alarcón Graciela S, Ramsey-Goldman Rosalind, Reveille John D, Vila Luis M, Petri Michelle, Kimberly Robert P, Feng Xuebing, Sun Lingyun, Shen Nan, Li Wei, Lu Jian-Xin, Wakeland Edward K, Li Quan-Zhen, Yang Wanling, Lau Yu-Lung, Liu Fei-Lan, Chang Deh-Ming, Yu Chack-Yung, Song Yeong W, Tsao Betty P, Criswell Lindsey A
Abstract excerpt
OBJECTIVE: The increased risk of thrombosis in systemic lupus erythematosus (SLE) may be partially explained by interrelated genetic pathways for thrombosis and SLE. The present study was undertaken to investigate whether 33 established and novel single-nucleotide polymorphisms (SNPs) in 20 genes involved in hemostasis pathways that have been associated with deep venous thrombosis (DVT) in the general population...
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