Article
[Analysis of gene expression data regulated by clock-genes: methodological approach and optimization].
Pathologie-biologie - 1 Oct 2013
Vuillaume M-L, Kwiatkowski F, Uhrhammer N, Bidet Y, Bignon Y-J
Abstract excerpt
BACKGROUND: In microarray data, wide-scale correlations are numerous and increase the number of genes correlated to a test condition (phenotype, mutation status, etc.) either positively or negatively. Several methods have been developed to limit the effect of such correlations on the false discovery rate, but these may reject too many genes that have a mild or indirect impact on the studied condition. We propose...
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