Article

Likelihood-based Tests for Detecting Circadian Rhythmicity and Differential Circadian Patterns in Transcriptomic Applications

2021-02-24

Abstract excerpt

Circadian rhythmicity in transcriptomic profiles has been shown in many physiological processes, and the disruption of circadian patterns has been founded to associate with several diseases. In this paper, we developed a series of likelihood-based methods to detect (i) circadian rhythmicity (denoted as LR rhythmicity) and (ii) differential circadian patterns comparing two experimental conditions (denoted as LR dif...

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Literature Corpus work: a6a12049-1880-5286-b8ca-857e97eb00f7
DOI: 10.1101/2021.02.23.432538

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