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Article

AMP-Activated Protein Kinase Is Required for the Macropinocytic Internalization of Ebolavirus

1 Nov 2012

Abstract excerpt

Identification of host factors that are needed for Zaire Ebolavirus (EBOV) entry provides insights into the mechanism(s) of filovirus uptake, and these factors may serve as potential antiviral targets. In order to identify novel host genes and pathways involved in EBOV entry, gene array findings in the National Cancer Institute's NCI-60 panel of human tumor cell lines were correlated with permissivity for EBOV...

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PMID: 23115293
DOI: 10.1128/jvi.01634-12

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