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Identification of novel cellular targets for therapeutic intervention against Ebola virus infection by siRNA screening

1 Jun 2009

Abstract excerpt

While much progress has been made in developing drugs against a few prominent viruses such as HIV, few examples exist for emerging infectious agents. In some cases broad spectrum anti-viral drugs, such as ribavirin, are effective, but for some groups of viruses, these show little efficacy in animal models. Traditional methods focus on screening small molecule libraries to identify drugs that target virus factors,...

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PMID: 20930947
DOI: 10.1002/ddr.20303

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