Lymphangioleiomyomatosis - a wolf in sheep's clothing.

Abstract excerpt

Lymphangioleiomyomatosis (LAM) is a rare progressive lung disease of women. LAM is caused by mutations in the tuberous sclerosis genes, resulting in activation of the mTOR complex 1 signaling network. Over the past 11 years, there has been remarkable progress in the understanding of LAM and rapid translation of this knowledge to an effective therapy. LAM pathogenic mechanisms mirror those of many forms of human...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Proliferation
• Share to Lung
• Share to Lung Neoplasms