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Lymphangioleiomyomatosis: where endocrinology, immunology and tumor biology meet

6 Jul 2023

Abstract excerpt

Abstract: Lymphangioleiomyomatosis (LAM) is a cystic lung disease found almost exclusively in genetic females and caused by small clusters of smooth muscle cell tumors containing mutations in one of the two tuberous sclerosis genes (TSC1 or TSC2). Significant advances over the past 2-3 decades have allowed researchers and clinicians to more clearly understand the pathophysiology of LAM, and therefore better...

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PMID: 37410387
DOI: 10.1530/erc-23-0102

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