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Article

Treatment options for patients with brain metastases from EGFR/ALK-driven lung cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 May 2017

Doherty Mark K, Korpanty Grzegorz J, Tomasini Pascale, Alizadeh Moein, Jao Kevin, Labbé Catherine, Mascaux Celine M, Martin Petra, Kamel-Reid Suzanne, Tsao Ming-Sound, Pintilie Melania, Liu Geoffrey, Bradbury Penelope A, Feld Ronald, Leighl Natasha B, Chung Caroline, Shepherd Frances A

Abstract excerpt

INTRODUCTION: Brain metastases in EGFR/ALK-driven NSCLC frequently pose treatment dilemmas. Tyrosine kinase inhibitors (TKIs) can control extracranial disease, but radiotherapy is often required for intracranial control. We aimed to evaluate the impact of first-line whole brain radiotherapy (WBRT), stereotactic radiotherapy (SRS) or TKI alone on outcomes of patients with brain metastases from EGFR/ALK-driven...

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Source

Identifiers

PMID: 28363487
DOI: 10.1016/j.radonc.2017.03.007

Genes

ALK
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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