Hopeahainol <scp>A</scp> attenuates memory deficits by targeting β‐amyloid in <scp>APP</scp>/<scp>PS</scp>1 transgenic mice

Abstract excerpt

Increasing evidence demonstrates that amyloid beta (Aβ) elicits mitochondrial dysfunction and oxidative stress, which contributes to the pathogenesis of Alzheimer's disease (AD). Identification of the molecules targeting Aβ is thus of particular significance in the treatment of AD. Hopeahainol A (HopA), a polyphenol with a novel skeleton obtained from Hopea hainanensis, is potentially...

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