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Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus

6 Nov 2007

Abstract excerpt

BACKGROUND: Community acquired (CA) methicillin-resistant Staphylococcus aureus (MRSA) increasingly causes disease worldwide. USA300 has emerged as the predominant clone causing superficial and invasive infections in children and adults in the USA. Epidemiological studies suggest that USA300 is more virulent than other CA-MRSA. The genetic determinants that render virulence and dominance to USA300 remain unclear....

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PMID: 17986343
DOI: 10.1186/1471-2180-7-99

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