Article
Characterization of the functional domains of the SloR metalloregulatory protein in Streptococcus mutans.
Journal of bacteriology - 1 Jan 2013
Haswell Jeffrey R, Pruitt Benjamin W, Cornacchione Louis P, Coe Christopher L, Smith Evan G, Spatafora Grace A
Abstract excerpt
Streptococcus mutans is a commensal member of the healthy plaque biofilm and the primary causative agent of dental caries. The present study is an investigation of SloR, a 25-kDa metalloregulatory protein that modulates genes responsible for S. mutans-induced cariogenesis. Previous studies of SloR homologues in other bacterial pathogens have identified three domains critical to repressor functionality: an...
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