Article
Health and production traits in bovine are associated with single nucleotide polymorphisms in the NOD2 gene.
Genetics and molecular research : GMR - 17 Apr 2015
Wang W, Cheng L, Yi J, Gan J, Tang H, Fu M Z, Wang H, Lai S J
Abstract excerpt
The NOD2 gene plays a fundamental role in initiating the inflammatory and subsequent immune response. NOD2 was previously identified as a susceptibility locus for inflammatory bowel diseases in humans. In this study, we detected 2 mutations in exon 12 (A→T, G→A) among 5 cattle breeds (N = 315) and analyzed their associations with production traits and genetic resistance against bovine mastitis in Chinese Holstein...
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