Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell type-dependent requirement of autophagy in HSV-1 antiviral defense.

Autophagy - 1 Feb 2013

Yordy Brian, Iwasaki Akiko

Abstract excerpt

Type I interferons (IFNs) are induced during most viral infections and are considered to be the primary and universal means of innate viral control. However, several other innate mechanisms, including autophagy, have recently been shown to play an important role in antiviral defense. In our recent study, we utilized a herpes simplex virus 1 (HSV-1) infection model to investigate the relationship between cell type...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Ganglia, Spinal
Share to Herpesvirus 1, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Innate

Share to Neurons

Share to Organ Specificity

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 23095715
DOI: 10.4161/auto.22506
PMCID: PMC3552887

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell type-dependent requirement of autophagy in HSV-1 antiviral defense.PMID 23095715Read ↗

A Neuron-Specific Role for Autophagy in Antiviral Defense against Herpes Simplex VirusSemantic proximity Read ↗

Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory NeuronsSemantic proximity Read ↗

Autophagy and viral neurovirulenceSemantic proximity Read ↗

Herpes Simplex Virus Type I Induces an Incomplete Autophagic Response in Human Neuroblastoma CellsSemantic proximity Read ↗

Investigating the role of autophagy in herpes simplex encephalitisSemantic proximity Read ↗

Herpes Simplex Virus type 1 inhibits autophagy in glial cells but requires ATG5 for the success of viral replicationSemantic proximity Read ↗

Basal Autophagy Is Required for Herpes simplex Virus-2 InfectionSemantic proximity Read ↗

An Intrinsic Host Defense against HSV-1 Relies on the Activation of Xenophagy with the Active Clearance of Autophagic ReceptorsSemantic proximity Read ↗

Herpes simplex virus interference with immunity: Focus on dendritic cellsSemantic proximity Read ↗

The ICP0 Protein of Herpes Simplex Virus 1 (HSV-1) Downregulates Major Autophagy Adaptor Proteins Sequestosome 1 and Optineurin during the Early Stages of HSV-1 InfectionSemantic proximity Read ↗

Local Immune Control of Latent Herpes Simplex Virus Type 1 in Ganglia of Mice and ManSemantic proximity Read ↗

Chikungunya virus–induced autophagy delays caspase-dependent cell deathSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.