Article
Herpes Simplex Virus Type I Induces an Incomplete Autophagic Response in Human Neuroblastoma Cells
18 Jun 2012
Abstract excerpt
Autophagy is a homeostatic process involved in the turnover or elimination of cytoplasmic components, damaged organelles, and protein aggregates via a lysosomal degradation mechanism. Autophagy also provides a mechanism of innate immunity, known as xenophagy, designed to protect cells from intracellular pathogens, but it may unfortunately be subverted to act as a pro-viral pathway facilitating the replication of...
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