Article
Exploring ankylosing spondylitis-associated ERAP1, IL23R and IL12B gene polymorphisms in subphenotypes of psoriatic arthritis.
Rheumatology (Oxford, England) - 1 Feb 2013
Jadon Deepak, Tillett William, Wallis Dinny, Cavill Charlotte, Bowes John, Waldron Nicola, Dixon Anna, Sengupta Raj, Barton Anne, Korendowych Eleanor, McHugh Neil J
Abstract excerpt
OBJECTIVE: To ascertain whether AS-associated polymorphisms of ERAP1, IL23R and IL12B genes associate with subphenotypes of PsA, particularly axial radiographic disease once stratified by HLA-B27 and HLA-Cw*0602 status. METHODS: rs30187 (ERAP1 gene), rs6887695 (IL12B gene), rs11209026 and rs7530511 (IL23R gene) single nucleotide polymorphisms were genotyped in 263 PsA cases from a prospective cohort and compared...
Read the complete abstract on PubMed