Article
A minimal bacterial RNase J-based degradosome is associated with translating ribosomes.
Nucleic acids research - 7 Jan 2013
Redko Yulia, Aubert Sylvie, Stachowicz Anna, Lenormand Pascal, Namane Abdelkader, Darfeuille Fabien, Thibonnier Marie, De Reuse Hilde
Abstract excerpt
Protein complexes directing messenger RNA (mRNA) degradation are present in all kingdoms of life. In Escherichia coli, mRNA degradation is performed by an RNA degradosome organized by the major ribonuclease RNase E. In bacteria lacking RNase E, the existence of a functional RNA degradosome is still an open question. Here, we report that in the bacterial pathogen Helicobacter pylori, RNA degradation is directed by...
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