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Article

KRAS mutations are associated with specific morphologic features in colon cancer.

Journal of clinical gastroenterology - 1 Jul 2013

Gunal Armagan, Hui Pei, Kilic Selim, Xu Ruliang, Jain Dhanpat, Mitchell Kisha, Robert Marie, Kenney Barton

Abstract excerpt

BACKGROUND: Mutations in the KRAS gene occur at an early stage in the development of colorectal carcinoma. Importantly, KRAS mutation predicts resistance to anti-epidermal growth factor receptor therapy in stage IV disease. GOALS: The aim of the current study is to correlate histologic features of colon cancer with the presence of KRAS mutations. STUDY: Tumor tissue from 145 colon cancer resections was tested for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23090042
DOI: 10.1097/MCG.0b013e3182703030

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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