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Marrow stromal cells, mitosis, and neuronal differentiation: stem cell and precursor functions.

Stem cells (Dayton, Ohio) - 1 Jan 2003

Muñoz-Elías Guillermo, Woodbury Dale, Black Ira B

Abstract excerpt

To define relationships among marrow stromal cells (MSCs), multipotential progenitors, committed precursors, and derived neurons, we examined differentiation, mitosis, and apoptosis in vitro. Neural induction medium morphologically converted over 70% of MSCs to typical neurons, which expressed tau, neuronal nuclear antigen, neuron-specific enolase, and TUC-4 within 24 hours. A subset decreased fibronectin...

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PMID: 12832697
DOI: 10.1634/stemcells.21-4-437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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