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Article

Impact of STAT3 phosphorylation on the clinical effectiveness of anti-EGFR-based therapy in patients with metastatic colorectal cancer.

Clinical colorectal cancer - 1 Mar 2013

Dobi Erion, Monnien Franck, Kim Stefano, Ivanaj Arben, N'Guyen Thiery, Demarchi Martin, Adotevi Olivier, Thierry-Vuillemin Antoine, Jary Marie, Kantelip Bernadette, Pivot Xavier, Godet Yann, Degano Severine Valmary, Borg Christophe

Abstract excerpt

UNLABELLED: Half of patients with KRAS wild-type colorectal cancer do not benefit from adding anti-epithelial growth factor receptor (EGFR) to standard chemotherapy regimens. This retrospective study was performed in 94 patients with metastatic colorectal cancer (mCRC) treated in the second line with cetuximab and chemotherapy. Signal transducer and activator of transcription 3 (STAT3) phosphorylation in tumor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23083634
DOI: 10.1016/j.clcc.2012.09.002

Genes

EGFR
STAT3
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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