Article
Prognostic value of cetuximab-related skin toxicity in metastatic colorectal cancer patients and its correlation with parameters of the epidermal growth factor receptor signal transduction pathway: results from a randomized trial of the GERMAN AIO CRC Study Group.
International journal of cancer - 1 Jan 2013
Stintzing Sebastian, Kapaun Christine, Laubender Rüdiger Paul, Jung Andreas, Neumann Jens, Modest Dominik Paul, Giessen Clemens, Moosmann Nicolas, Wollenberg Andreas, Kirchner Thomas, Heinemann Volker
Abstract excerpt
Skin toxicity is a frequent adverse event of epidermal growth factor receptor (EGFR) targeting agents. Occurrence of cetuximab-induced skin toxicity (Cet-ST) correlates with better treatment response and longer survival times. Molecular markers predicting Cet-ST are still missing. This investigation analyzed the value of Cet-ST for treatment efficacy in a randomized trial comparing cetuximab plus...
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