Article
Evaluation of 14 organic solvents and carriers for screening applications in zebrafish embryos and larvae.
PloS one - 1 Jan 2012
Maes Jan, Verlooy Lien, Buenafe Olivia E, de Witte Peter A M, Esguerra Camila V, Crawford Alexander D
Abstract excerpt
Zebrafish are rapidly growing in popularity as an in vivo model system for chemical genetics, drug discovery, and toxicology, and more recently also for natural product discovery. Experiments involving the pharmacological evaluation of small molecules or natural product extracts in zebrafish bioassays require the effective delivery of these compounds to embryos and larvae. While most samples to be screened are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.