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Article

Small molecule screening in the zebrafish.

Methods (San Diego, Calif.) - 1 Jul 2006

Murphey R D, Zon L I

Abstract excerpt

The zebrafish is an ideal organism for small molecule studies. The ability to use the whole organism allows complex in vivo phenotypes to be assayed and combines animal testing with screening. Embryos are easily treatable by waterborne exposure. The small size and abundance of embryos make zebrafish suitable for screening in a high-throughput manner in 96- or 48-well plates. Zebrafish embryos have successfully...

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PMID: 16877005
DOI: 10.1016/j.ymeth.2005.09.019

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