Article
Systematic approaches to toxicology in the zebrafish.
Annual review of pharmacology and toxicology - 1 Jan 2012
Peterson Randall T, Macrae Calum A
Abstract excerpt
As the current paradigms of drug discovery evolve, it has become clear that a more comprehensive understanding of the interactions between small molecules and organismal biology will be vital. The zebrafish is emerging as a complement to existing in vitro technologies and established preclinical in vivo models that can be scaled for high-throughput. In this review, we highlight the current status of zebrafish...
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