Article
Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells.
Stem cells (Dayton, Ohio) - 1 Jan 2013
White Mark P, Rufaihah Abdul J, Liu Lei, Ghebremariam Yohannes T, Ivey Kathryn N, Cooke John P, Srivastava Deepak
Abstract excerpt
Recent evidence suggests human embryonic stem cell (hESC) and induced pluripotent stem (iPS) cell lines have differences in their epigenetic marks and transcriptomes, yet the impact of these differences on subsequent terminally differentiated cells is less well understood. Comparison of purified, homogeneous populations of somatic cells derived from multiple independent human iPS and ES lines will be required to...
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