Article
Renal xenotransplantation: experimental progress and clinical prospects.
Kidney international - 1 Apr 2017
Wijkstrom Martin, Iwase Hayato, Paris Wayne, Hara Hidetaka, Ezzelarab Mohamed, Cooper David K C
Abstract excerpt
There are >100,000 patients waiting for kidney transplants in the United States and a vast need worldwide. Xenotransplantation, in the form of the transplantation of kidneys from genetically engineered pigs, offers the possibility of overcoming the chronic shortage of deceased and living human donors. These genetic manipulations can take the form of (i) knockout of pig genes that are responsible for the...
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