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Article

Elicitation of an oxidase activity in bacterial luciferase by site-directed mutation of a noncatalytic residue.

The Journal of biological chemistry - 15 Mar 1990

Xi L, Cho K W, Herndon M E, Tu S C

Abstract excerpt

Flavin-dependent external monooxygenases and oxidases could catalyze the same flavin oxidation reaction involving distinct mechanisms. To gain insights into enzyme structure-function relationship, site-directed mutagenesis was carried out for Vibrio harveyi luciferase, a monooxygenase. The substitution of the alpha subunit cysteine 106 by alanine shows unambiguously that the alphaCys106 is not essential to...

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PMID: 2307667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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