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<i>Burkholderia pseudomallei</i>kills<i>Caenorhabditis elegans</i>through virulence mechanisms distinct from intestinal lumen colonization

1 Oct 2012

Abstract excerpt

The nematode Caenorhabditis elegans is hypersusceptible to Burkholderia pseudomallei infection. However, the virulence mechanisms underlying rapid lethality of C. elegans upon B. pseudomallei infection remain poorly defined. To probe the host-pathogen interaction, we constructed GFP-tagged B. pseudomallei and followed bacterial accumulation within the C. elegans intestinal lumen. Contrary to slow-killing by most...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23076282
DOI: 10.4161/viru.21808

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