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Concise Review: Defining Characteristics of Mammalian Spermatogenic Stem Cells

16 Oct 2012

Abstract excerpt

The enormous number of sperms produced daily and over the lifetime of mammals requires a stable source of stem cells that give rise to progenitor cells that proceed through spermatogenesis. Spermatogenic stem cells develop from primitive germ cells that occupy the developing gonad. A transplantation assay was developed for the spermatogenic stem cells, and it remains the only functional measure of authentic stem...

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PMID: 23074087
DOI: 10.1002/stem.1253

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