Article
SNP array analysis reveals novel genomic abnormalities including copy neutral loss of heterozygosity in anaplastic oligodendrogliomas.
PloS one - 1 Jan 2012
Idbaih Ahmed, Ducray François, Dehais Caroline, Courdy Célia, Carpentier Catherine, de Bernard Simon, Uro-Coste Emmanuelle, Mokhtari Karima, Jouvet Anne, Honnorat Jérôme, Chinot Olivier, Ramirez Carole, Beauchesne Patrick, Benouaich-Amiel Alexandra, Godard Joël, Eimer Sandrine, Parker Fabrice, Lechapt-Zalcman Emmanuelle, Colin Philippe, Loussouarn Delphine, Faillot Thierry, Dam-Hieu Phong, Elouadhani-Hamdi Selma, Bauchet Luc, Langlois Olivier, Le Guerinel Caroline, Fontaine Denys, Vauleon Elodie, Menei Philippe, Fotso Marie Janette Motsuo, Desenclos Christine, Verrelle Pierre, Verelle Pierre, Ghiringhelli François, Noel Georges, Labrousse François, Carpentier Antoine, Dhermain Frédéric, Delattre Jean-Yves, Figarella-Branger Dominique
Abstract excerpt
Anaplastic oligodendrogliomas (AOD) are rare glial tumors in adults with relative homogeneous clinical, radiological and histological features at the time of diagnosis but dramatically various clinical courses. Studies have identified several molecular abnormalities with clinical or biological relevance to AOD (e.g. t(1;19)(q10;p10), IDH1, IDH2, CIC and FUBP1 mutations).To better characterize the clinical and...
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