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Article

Genetic disorders of surfactant homeostasis.

Biology of the neonate - 1 Jan 2005

Whitsett Jeffrey A, Wert Susan E, Xu Yan

Abstract excerpt

Adaptation to air breathing at birth requires the precise orchestration of cellular processes to initiate fluid clearance, enhance pulmonary blood flow, and to synthesize and secrete pulmonary surfactant needed to reduce surface tension at the air-liquid interface in the alveoli. Genetic programs regulating the synthesis of the surfactant proteins and lipids required for the production and function of pulmonary...

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Source

Identifiers

PMID: 15985750
DOI: 10.1159/000084875

Genes

ABCA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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