Article
NDRG2 and PRA1 interact and synergistically inhibit T-cell factor/β-catenin signaling.
FEBS letters - 16 Nov 2012
Kim Jong-Tae, Kim Jae Wha, Kang Yun Hee, Kim Kwang Dong, Lee Seon-Jin, Choi Seung-Chul, Kim Kwang Soo, Chae Suhn-Kee, Kim Jung Woo, Lim Jong-Seok, Lee Hee Gu
Abstract excerpt
NDRG2 is a member of the N-myc downstream regulated gene (NDRG) family, implicated in cell growth and differentiation. Investigation of NDRG2 molecular interactions by yeast two-hybrid screening identified prenylated Rab acceptor-1 (PRA1), involved in vesicle trafficking and protein transport, as binding partner. Binding of NDRG2 (and NDRG1-4) with PRA1 in vitro was confirmed by GST pull-down assay and...
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