Article
Ndrg1 promotes adipocyte differentiation and sustains their function.
Scientific reports - 3 Aug 2017
Cai Kai, El-Merahbi Rabih, Loeffler Mona, Mayer Alexander E, Sumara Grzegorz
Abstract excerpt
Adipocytes play a central role in maintaining metabolic homeostasis in the body. Differentiation of adipocyte precursor cells requires the transcriptional activity of peroxisome proliferator-activated receptor-γ (Pparγ) and CCAAT/enhancer binding proteins (C/Ebps). Transcriptional activity is regulated by signaling modules activated by a plethora of hormones and nutrients. Mechanistic target of rapamacin...
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