Article
Different biological activities in conditioned media control the expression of a variety of neuropeptides in cultured sympathetic neurons.
Neuron - 1 Feb 1990
Nawa H, Sah D W
Abstract excerpt
An intriguing question regarding neuronal development is how neurons choose which neurotransmitter and/or peptide to express among over 40 candidates. We find that heart cell conditioned medium (CM) induces a number of neuropeptides and/or their precursor mRNAs, as well as acetylcholine, in cultu...
Topics
- Animals
- Cells, Cultured
- Chromatography, High Pressure Liquid
- Culture Media
- Immunohistochemistry
- Myocardium
- Neurons
- Neuropeptides
- Phenotype
- Protein Precursors
- RNA, Messenger
- Radioimmunoassay
- Rats
- Rats, Inbred Strains
- Sympathetic Nervous System
