Article
The influence of omeprazole on platelet inhibition of clopidogrel in various CYP2C19 mutant alleles.
Genetic testing and molecular biomarkers - 1 Nov 2012
Liu Qian, Dang Da-Sheng, Chen Yu-Feng, Yan Ming, Shi Guo-Bing, Zhao Qing-Chun
Abstract excerpt
Currently, concerns of clopidogrel and proton pump inhibitors (especially omeprazole) interaction are raised, because they are both metabolized by CYP2C19. What is more, omeprazole can also inhibit the activity of CYP2C19. The study was to compare the influence of omeprazole on platelet inhibitio...
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