Article
Human osteosarcoma CD49f(-)CD133(+) cells: impaired in osteogenic fate while gain of tumorigenicity.
Oncogene - 5 Sept 2013
Ying M, Liu G, Shimada H, Ding W, May W A, He Q, Adams G B, Wu L
Abstract excerpt
The biological relationships among self-renewal, tumorigenicity and lineage differentiation of human osteosarcoma-initiating cells (OSIC) remain elusive, making it difficult to identify and distinguish OSIC from osteosarcoma-forming cells (OSFC) for developing OSIC-targeted therapies. Using a new...
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