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Article

Genotypes B and C hepatocellular carcinoma-associated hepatitis B virus pre-S mutants: their detection among F1b and A2 - but not F4 - isolates from Argentina.

Journal of viral hepatitis - 1 Nov 2012

Trinks J, Frías S, Frider B, Alessio A, Pozzati M, Daleoso G, León L, Batalla V M, Díaz A, Ameigeiras B, Oubiña J R

Abstract excerpt

Prevalence rates of hepatocellular carcinoma (HCC)-associated hepatitis B virus (HBV) pre-S mutants among most genotypes are still lacking. In this study, viral (sub)genotypes of 70 Argentine nucleotide sequences (33 newly obtained) were determined by phylogenetic analysis, and the presence of such mutants was assessed in the American continent for the first time. Nucleotide substitutions of the pre-S2 start...

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PMID: 23043389
DOI: 10.1111/j.1365-2893.2012.01620.x

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