Article
Genetic determinants of "cognitive impairment, no dementia".
Journal of Alzheimer's disease : JAD - 1 Jan 2013
Dubé Joseph B, Johansen Christopher T, Robinson John F, Lindsay Joan, Hachinski Vladimir, Hegele Robert A
Abstract excerpt
Dementia is a heritable condition with devastating effects on both patients and their caregivers. Studies have identified genetic variants associated with increased susceptibility to late-onset Alzheimer disease (AD)-related dementia; however, no studies have assessed whether genetic variation is associated with the early stages of cognitive decline. Given that cerebrovascular disease is an established mechanism...
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