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Article

STAT6‐dependent and ‐independent mechanisms in T h2 polarization

8 Oct 2012

Abstract excerpt

Th2 cells play a key role in directing immune responses against helminths. Additionally, Th2 cells are crucial for many types of allergic reactions. Whereas the molecular mechanisms underlying the differentiation of other types of Th cells are well understood, Th2 differentiation is still a controversial topic. IL-4 and its downstream transcription factor signal transducer and activator of transcription (STAT)6...

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PMID: 23041833
DOI: 10.1002/eji.201242433

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