Associations between Adiponectin Gene Variability, Proinflammatory and Angiogenetic Markers: Implications for Microvascular Disease Development in Type 2 Diabetes Mellitus?

doi:10.2174/1570161116666180108113825

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Article

Associations between Adiponectin Gene Variability, Proinflammatory and Angiogenetic Markers: Implications for Microvascular Disease Development in Type 2 Diabetes Mellitus?

Current vascular pharmacology - 1 Jan 2019

Kollia Christina, Antonopoulos Alexios S, Siasos Gerasimos, Konsola Theodosia, Oikonomou Evangelos, Gouliopoulos Nikolaos, Tsigkou Vasiliki, Papapanagiotou Aggeliki, Kassi Eva, Tentolouris Nicholas, Katsiki Niki, Vavuranakis Manolis, Papavassiliou Athanasios G, Tousoulis Dimitris

Abstract excerpt

BACKGROUND: Adiponectin gene (ADIPOQ) variability may affect the risk for type 2 diabetes mellitus (T2DM) but it remains unclear whether it is involved in microvascular complications. OBJECTIVE: To explore the impact of ADIPOQ variability on markers of inflammation and angiogenesis in T2DM. METHODS: Overall, 220 consecutive T2DM patients from our outpatient diabetic clinic were genotyped for G276T (rs1501299) and...

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PMID: 29308741
DOI: 10.2174/1570161116666180108113825

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ADIPOQ

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