Article
Evidence for association of bipolar disorder to haplotypes in the 22q12.3 region near the genes stargazin, IFT27 and parvalbumin.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2012
Nissen Stephanie, Liang Sherri, Shehktman Tatyana, Kelsoe John R, Greenwood Tiffany A, Nievergelt Caroline M, McKinney Rebecca, Shilling Paul D, Smith Erin N, Schork Nicholas J, Bloss Cinnamon S, Nurnberger John I, Edenberg Howard J, Foroud Tatiana, Koller Daniel L, Gershon Elliot S, Liu Chunyu, Badner Judith A, Scheftner William A, Lawson William B, Nwulia Evaristus A, Hipolito Maria, Coryell William, Rice John, Byerley William, McMahon Francis J, Berrettini Wade H, Potash James B, Zandi Peter P, Mahon Pamela B, McInnis Melvin G, Zöllner Sebastian, Zhang Peng, Craig David W, Szelinger Szabolics, Barrett Thomas B, Schulze Thomas G
Abstract excerpt
We have previously reported genome-wide significant linkage of bipolar disorder to a region on 22q12.3 near the marker D22S278. Towards identifying the susceptibility gene, we have conducted a fine-mapping association study of the region in two independent family samples, an independent case-control sample and a genome-wide association dataset. Two hundred SNPs were first examined in a 5 Mb region surrounding the...
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