Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drosophila S2 Cells Secrete Wingless on Exosome‐Like Vesicles but the Wingless Gradient Forms Independently of Exosomes

5 Oct 2012

Abstract excerpt

Wingless acts as a morphogen in Drosophila wing discs, where it specifies cell fates and controls growth several cell diameters away from its site of expression. Thus, despite being acylated and membrane associated, Wingless spreads in the extracellular space. Recent studies have focussed on identifying the route that Wingless follows in the secretory pathway and determining how it is packaged for release. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to Vector-Borne Animal Diseases
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23035643
DOI: 10.1111/tra.12016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Drosophila S2 Cells Secrete Wingless on Exosome‐Like Vesicles but the Wingless Gradient Forms Independently of ExosomesPMID 23035643Read ↗

Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex.Semantic proximity Read ↗

Microscopic and biochemical monitoring of endosomal trafficking and extracellular vesicle secretion in an endogenous in vivo modelSemantic proximity Read ↗

Microvilli-derived extracellular vesicles carry Hedgehog morphogenic signals for Drosophila wing imaginal disc developmentSemantic proximity Read ↗

Secretion and movement of wingless protein in the epidermis of the Drosophila embryo.Semantic proximity Read ↗

SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of Wntless.Semantic proximity Read ↗

Exosome Secretion — More Than Simple Waste Disposal? Implications for Physiology, Diagnostics and TherapeuticsSemantic proximity Read ↗

Q&A: What are exosomes, exactly?Semantic proximity Read ↗

Micro RNAs are minor constituents of extracellular vesicles and are hardly delivered to target cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.