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Article

Correlation between Slug transcription factor and miR-221 in MDA-MB-231 breast cancer cells

2 Oct 2012

Abstract excerpt

BACKGROUND: Breast cancer and its metastatic progression is mainly directed by epithelial to mesenchymal transition (EMT), a phenomenon supported by specific transcription factors and miRNAs. METHODS: In order to investigate a possible correlation between Slug transcription factor and miR-221, we performed Slug gene silencing in MDA-MB-231 breast cancer cells and evaluated the expression of genes involved in...

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PMID: 23031797
DOI: 10.1186/1471-2407-12-445

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